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Nat Med (2018) 24(10):15325

Common and potential side effects include: Skin irritation : Redness, itching, rashes, or allergic reactions where the patch sits, especially with daily use Cardiovascular effects : Bitter orange extract can increase heart rate and blood pressure Digestive issues : Green tea extract may cause upset stomach or headaches Sleep problems : Caffeine content from green tea extract can disrupt sleep Liver concerns : Garcinia cambogia has been linked to liver problems in some cases Unknown risks : Lack of regulation means uncertain ingredient quality and quantities The bigger concern is that these products arent regulated in the same way as prescription medications

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Brace yourself: Construction and road closures are slated to begin this fall

Studies of the secretion of corticotropin releasing factor and arginine vasopressin into hypophyseal portal circulation of the conscious sheep

For employers, these developments could lead to shifts in formulary decisions and cost-sharing strategies