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This article examines the emerging evidence, proposed mechanisms involving brain reward pathways, and important safety considerations for clinicians and patients navigating this investigational area

Ozempic (injection) and Rybelsus (tablet) are FDA-approved to treat type 2 diabetes, and Wegovy is approved for weight loss

Anti-rebound strategies should be integrated into the clinical pathway, including intensified lifestyle maintenance and, where appropriate, sequential metformin to maintain metabolic stability

However, it is worth noting that most preclinical studies do not incorporate a dose titration phase, a gradual increase to the therapeutic maintenance dose, which is standard in clinical settings

You may also hear people refer to them as GLP-1 receptor agonists (GLP-1 RAs) or GLP-1 agonists

Electronic Health Record (EHR): Use a flexible, API-friendly platform such as Healthie which supports both integration and customization