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More potent peptides such as liraglutide, semaglutide, and tirzepatide may have greater antiinflammatory effects, consistent with correlations between CRP and weight loss seen in lifestyle interventions and bariatric surgery (20)

This review adopts a biopsychosocial perspective to examine how GLP-1 RAs interact with eating behavior, mood, identity, and self-regulation, particularly in individuals with binge eating disorder (BED) or other psychiatric comorbidities

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Lastly, we present considerations to accurately interpret these data and outline key knowledge gaps for further investigation

GLP-1 receptor agonists (GLP-1 RA) are a class of medications originally developed to treat type 2 diabetes, but have since gained widespread attention for their effects on weight loss and metabolic health