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A pilot-controlled trial of insulin-like growth factor-1 in children with Phelan-McDermid syndrome

In the future, the molecular mechanisms utilised by the microbiota should be explored through the collection of more samples for macrogenomic sequencing

These were specifically evaluated for safe, consistent absorption during clinical development

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Results for Study 3 At the end of the 12-week intensive lifestyle intervention lead-in, for patients who subsequently entered the randomized treatment period (n=579), the average body weight loss due to lifestyle was 6.9% (Week -12 to Week 0)

Specific author contributions: A.M.E