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The mean age of adult patients was 58 years, 4% were 75 years or older and 54% were male
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High Fat-Fed Diabetic Mice Present With Profound Alterations of the Osteocyte Network

however, metabolically stressed Glp1r cell/ :Gcgr cell/ mice exhibit impaired oral and IP glucose intolerance as compared to HFD-fed controls ( + alpha-cells, and a greater dependency on GLP-1R signaling for insulin secretion, as compared to islets from healthy donors ( + :glucagon + alpha-cells with the onset of diabetes in db/db mice as compared to normal mice (86)

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