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Adults with overweight or obesity lost more weight with the GIP/GLP-1 dual agonist tirzepatide than the GLP-1 receptor agonist semaglutide, according to findings published in JAMA Internal Medicine

Upon injection, it binds directly to GLP-1 receptors located in the brain's satiety centers, drastically reducing hunger signals and putting an end to compulsive psychological cravings

11 (2021): 9891002, 10.1056/NEJMoa2032183

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Simultaneously, it enhances signaling from peptide YY, another satiety hormone, creating a dual effect that quiets both the physical sensation of hunger and the mental preoccupation with eating

However, if youre taking Ozempic, you may notice that certain foods dont agree with you