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Legare de receptorii GLP-1: Tirzepatide activeaz receptorii GLP-1 din pancreas, sistemul nervos central i tractul gastrointestinal, ceea ce duce la stimularea dependent de glucoz a secreiei de insulin i la suprimarea eliberrii glucagonului

Pregnant rodents were administered clinically equivalent doses of prednisone daily by oral gavage during gestation days (GDs) 020 in rats and GD018 mice, and their offspring were fed a high-fat diet from postnatal weeks 812

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