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Wallner M, Kolesnik E, Ablasser K, Khafaga M, Wakula P, Ljubojevic S, Thon-Gutschi EM, Sourij H, Kapl M, Edmunds NJ, Kuzmiski JB, Griffith DA, Knez I, Pieske B, von Lewinski D
An increased risk for thyroid autoimmunity has been reported in adults with T1D and late-onset autoimmune-induced diabetes (1013)

Most women experience a profound sensation of heavy legs due to the constant inflammation trapped in their thighs and calves
10.1172/JCI91761 31 DavisE

Therefore, the activation of the IGF-2/IGF-1R axis may contribute to -cell survival in response to GLP-1, and importantly, the increased IGF-2 secretion may be essential for triggering this response, as also observed in embryonic development (41)
References Amato, A., Baldassano, S., Liotta, R., et al
