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In a significant milestone for type 2 diabetes care, Novo Nordisk has unveiled full results from its SOUL cardiovascular outcomes trial, confirming that oral semaglutide (14 mg) reduces the risk of major adverse cardiovascular events (MACE) by 14 per cent compared to placebo in adults with type 2 diabetes and existing cardiovascular and/or chronic kidney disease.The findings, presented at the American College of Cardiology's (ACC) Annual Scientific Session and Expo in Chicago, and simultaneously published in the New England Journal of Medicine, mark a major advancement in cardiometabolic treatment

Discover why UK guidance generally advises against combining these medications, the evidence behind this recommendation, potential risks, and more effective alternative treatment strategies for optimal glycaemic control.

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