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Eligible participants were adults (18 years) without diabetes and with a body-mass index (BMI) of 30 kg/m 2 or more

If you smoke, cessation is strongly advised, as tobacco use weakens the lower esophageal sphincter and worsens reflux

The Daily is made by Rachel Quester, Lynsea Garrison, Clare Toeniskoetter, Paige Cowett, Michael Simon Johnson, Chris Wood, Jessica Cheung, Stella Tan, Alexandra Leigh Young, Lisa Chow, Eric Krupke, Marc Georges, M.J

It is naturally activated by GLP-1, a hormone released after eating

An additional phase II trial, ENERGIZE, has sought to identify the mechanism behind the apparent synergy (146), the findings of which may influence whether such a combination is advanced further

Drugs able to activate a number of receptors seem to perform better