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New aspects of an old drug: metformin as a glucagon-like peptide 1 (GLP-1) enhancer and sensitiser
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Nosemaglutide is designed for once-weekly dosing based on its seven-day half-life and clinical trial evidence
Investigations into biased agonism, where medications are designed to selectively activate beneficial GLP-1 receptor pathways while minimizing those that cause side effects, could eventually produce GLP-1 medications with significantly reduced dry mouth profiles
