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In terms of results, the Wegovy pill (13.6% average weight loss at 64 weeks) performed slightly better than orforglipron (11.112.4% at 72 weeks)

The short answer is yes, most people can, but with some important considerations

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Its effectiveness is clear: Dr Chahal points to research that has found a weekly 2.4mg dose of semaglutide can trigger up to a 15 per cent reduction in body weight in the space of six to nine months
DN is primarily attributed to chronic hyperglycemia-induced microvascular damage in the kidneys, which leads to impaired renal perfusion and subsequently triggers inflammation, oxidative stress, glomerulosclerosis and tubulointerstitial fibrosis, ultimately resulting in progressive and irreversible renal dysfunction

Despite advances in medical interventions, the recurrence of stroke, particularly in patients with comorbid conditions like diabetes mellitus and obesity, is alarmingly high
