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However, injectable therapies generally show slightly greater HbA1c reduction and weight loss

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These pleiotropic actions, combined with robust analgesic and antifibrotic effects, support GLP-1 analogues as a promising new therapeutic class for OA

Au HCT, Zheng YJ, Le GH, Wong S, Teopiz KM, Kwan ATH, Gill H, Badulescu S, Valentino K, Rosenblat JD, Mansur RB, McIntyre RS (2025) Association of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and neurogenesis: a systematic review

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