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Compounded semaglutide has been safely used by thousands of patients since GLP-1 therapy became mainstream, with safety profiles matching brand-name products

Reuters

Theyre not FDA-approved but are often used when there is a shortage of FDA-approved medication

Diseases such as CHI and MEN-1, which are clinically uncommon and easily underdiagnosed, have also been studied and molecular imaging has given them crossover implications

Any trial of an alternative GLP-1 agonist should occur under close medical supervision, ideally in a setting where emergency treatment is readily available