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Oral contraceptives and some antibiotics may be affected by delayed gastric emptying caused by semaglutide, potentially reducing their effectiveness

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In our previous work on combination treatment with an SGLT2 inhibitor and GLP1-RA, we found some baseline characteristics that might identify responders, and relatively low BMI and low insulin secretion were associated with greater bodyweight loss [73]

They work by mimicking the action of the GLP-1 hormone, which regulates appetite, insulin secretion, and blood sugar levels