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People with a Family History of thyroid cancer: The FDA has issued a boxed (black box warning for semaglutide based on animal studies that revealed that semaglutide may increase the risk of thyroid cancer

This was an observational study in a specific clinical population [consequently] randomised clinical trials are needed before GLP-1 medications can be recommended for treating addiction, he explained

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The FDA prescribing information for GLP-1 receptor agonists, including semaglutide, notes an increased risk of acute gallbladder disease (cholelithiasis, cholecystitis), which can present with jaundice and elevated liver enzymes that might be mistaken for direct liver injury

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[DOI] [PubMed] [Google Scholar] 38.Gorgojo-Martinez J.J., Mezquita-Raya P., Carretero-Gomez J., Castro A., Cebrian-Cuenca A., de Torres-Sanchez A., Garcia-de-Lucas M.D., Nunez J., Obaya J.C., Soler M.J., et al