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Glucagon-like peptide 1 (GLP1) receptor (GLP1R) agonists reduce body weight, glycaemia, blood pressure, postprandial lipaemia and inflammation actions that could contribute to the reduction of cardiovascular events

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GIP stimulates glucagon secretion (in a glucose-dependent manner) and inhibits gastric acid secretion, whereas GLP-1 inhibits glucagon secretion, slows gastric emptying, inhibits gastric acid secretion, and attenuates small bowel motility [1,2,77,79]

Titration involves starting at a very low dose and gradually increasing it over several months

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What does clinical research say about once-weekly versus twice-weekly GLP-1 dosing