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Slight deviations in systemic exposure can precipitate hypoglycemia (if exposure is too high) or loss of glycemic control (if exposure is too low), outcomes that are immediate and potentially life-threatening (Heinemann, 2002)

[DOI] [PMC free article] [PubMed] [Google Scholar] 164.Houttu V, Grefhorst A, Cohn DM, et al

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