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People whose BMI is 40.0 or greater are sometimes categorized as severely obese. The CDC has more information about BMI, its uses and how to calculate it
Sources Jiang Y, et al

(Linong Ji) GLP-1

Grennan Drafting of the manuscript: Krista N

Reported Side Effects from Extended Use Data from clinical trials show that the safety profile of tirzepatide has some gastrointestinal symptoms

Certain nutrients and food components can trigger GLP-1 secretion from your intestinal L-cells