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98 Although located in the sinoatrial node, GLP-1 RAs influence the cardiovascular system through several other mechanisms, including the use of myocardial glucose, improvement of left ventricular function, myocardial ischaemic protection, increased heart rate, vasodilation, anti-atherosclerotic effects, and blood pressure reduction

Statistics and reproducibility Statistical analyses were performed using GraphPad Prism 9 software

Adems, se ha demostrado que el inhibidor de la DPP-4, linagliptina, disminuye la expresin de protenas relacionadas con la presencia de fibrosis miocrdica y los niveles de marcadores de estrs cardiomiocitario en un modelo de rata con cardiomiopata urmica71

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Ottman, N., et al., Pili-like proteins of Akkermansia muciniphila modulate host immune responses and gut barrier function

doi: 10.1186/s13195-021-00813-8 [DOI] [PMC free article] [PubMed] [Google Scholar] 33