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Participants taking the highest dose of orforglipron (36 mg) experienced a mean weight loss of 7.3 kg , or 7.9%, compared with 1.3 kg or 1.6% in the placebo group

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No, extensive research including large trials and real-world studies has not demonstrated an increased risk of pancreatic cancer with GLP-1 receptor agonist use

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In the pre-assessment phase, your anaesthetist will discuss how these medications might affect your anaesthesia, and a clear plan can be made to reduce any potential risks