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Furthermore, semaglutide 7.2 mg was associated with a greater likelihood of achieving body weight reduction of at least 25%, compared with semaglutide 2.4 mg (OR 2.4, 95% 1.63.5)
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Tirzepatide and semaglutide have broadly similar GI side effect profiles nausea, vomiting, and constipation being the primary tolerability concerns with some patients finding one more tolerable than the other
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Common symptoms include: Vomiting (often projectile or explosive) Watery diarrhea Nausea Stomach pain or cramps People with norovirus often experience vomiting and diarrhea multiple times a day, which can lead to dehydration
By 2026, it is widely regarded as the benchmark GLP-1 compound against which newer weight loss therapies are measured
