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To our knowledge, no retrospective studies have been conducted to assess the effectiveness of semaglutide at the doses used to treat obesity (ie, 1.7 and 2.4 mg). Researchers conducted a cohort study at a referral center for weight management and included 175 patients (mean age, 49.3 years

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At its core is Semaglutide, a powerful GLP-1 receptor agonist known to reduce appetite and support blood sugar regulation

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2.6 Sensitivity analysis and price threshold analysis We performed a univariate sensitivity analysis to evaluate the impact of changing key inputs in the model, including the discount rate, initial utility, time horizon, costs, and disutility scores (Supplementary Table S5)

Keywords: pediatric obesity, GLP-1 receptor agonists, semaglutide, adolescent weight management, pharmacotherapy, long-term safety, health equity, obesity treatment Introduction The global pediatric obesity epidemic represents one of the most pressing public health challenges of the 21st century