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First, different doses of ghrelin were used

This review delineates the multifaceted mechanisms by which GLP-1RAs exert ocular benefits, including retinal ganglion cell (RGC) rescue via calcium channel and GABAergic modulation, mitochondrial protection through PINK1/Parkin-mediated mitophagy and ERK1/2-HDAC6 signaling, as well as potent anti-inflammatory effects via cytokine reduction and immune cell recruitment inhibition

Further research has revealed that GLP-1RAs can significantly reduce the expression of various inflammatory factors associated with the occurrence of diabetic sarcopenia

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