glp-1 drug tirzepatide Use of the dual GIP/GLP-1 (Mounjaro, Zepbound) was associated with a significantly reduced risk of glaucoma compared with drugs among patients with type 2 diabetes, a large retrospective cohort Q&A: How Specific GLP-1s Impact

doi: 10.14814/phy2.14651 27 BiswasSCButeauJGreeneLA

Potential implications of the new pharmacotherapies on obesity management The mean WL in clinical trials with the most efficacious new obesity pharmacotherapies ranges between 15% and 25% at 1 year (and it may be even higher for some agents that have not reached weight plateau at study completion)

doi.org/10.3390/receptors4010002 Batista AF, Forny-Germano L, Clarke JR, et al

For context, metformin (the traditional first-line medication) typically produces 0.5-1.0 percentage point reductions

Similarly, cutting or modifying patches to adjust dosing is dangerous and should never be attempted, as this can cause rapid, uncontrolled drug release and potential overdose

Severe cases can turn into pseudo-obstruction or real small bowel blockage - a medical emergency that needs immediate attention