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One important consideration: research suggests that bioavailability may be up to 12% lower when injecting into the thigh compared to the abdomen

In 2020, medical studies highlighted that GLP-1 agonists like Ozempic could exacerbate symptoms of diabetic gastroparesis in patients with pre-existing conditions

Some patients had hypersensitivity reactions, including rash and mild swelling, but anaphylaxis was uncommon

P.SalaD.et al

Safety and efficacy of oral semaglutide versus dulaglutide in Japanese patients with type 2 diabetes (PIONEER 10): a multicentre, open-label, randomised, phase 3a trial

Clin Endocrinol 81(4):588592
