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Other important side effects and warnings include: Injection site reactions such as redness or itching Increased heart rate Hypoglycemia (uncommon with semaglutide alone but more likely when combined with insulin or sulfonylureas

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Carolyn Bramante, who works in the weight management clinic at the University of Minnesota says she still uses metformin "quite often" for patients with a host of weight-related issues, including type 2 diabetes, pre-diabetes, and obesity, too
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