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Apitegromab (SRK-015), an investigational new drug developed by Scholar Rock, is a fully human IgG4 monoclonal antibody that specifically binds to human Pro-GDF8 or latent GDF8 without binding to mature GDF8 or other closely related growth factors

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Sitagliptin is the first of a class of drugs to be approved that mimics the actions of the dipeptidyl peptidase-4 (DPP-4) enzyme.

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