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Hydroxyurea, a cornerstone of sickle cell treatment, is considered a teratogen, so it comes off the table

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I see a lot of women in this phase of life who have worked out and been healthy their whole lives and are frustrated with the weight gain theyre experiencing now, says Disha Narang, MD, an endocrinologist and the director of obesity medicine at Endeavor Health in Skokie, Illinois

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Generally, surrogate endpoints are expected to predict clinical benefits

10.3758/BF03193146 [DOI] [PubMed] [Google Scholar] 9.Summary of Revisions: Standards of Medical Care in Diabetes-2018