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Lactic acidosis: Though rare, Metformin can cause a dangerous condition called lactic acidosis, which requires immediate medical attention

[DOI] [PubMed] [Google Scholar] 31.Hogan A

But we were also curious about how GLP-1 and GIP impacted insulin and glucagon secretion. Researchers were surprised to find there were no differences with glycemic control even though the kidney disease patients were secreting more GLP-1 and GIP

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Nausea and Vomiting When it happens: Often worse when starting treatment and after increasing doses How to manage it: Eat smaller, more frequent meals
doi: 10.1016/j.yhbeh.2011.08.006
