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doi: 10.1016/j.jaac.2013.12.001

For that design to work, patients must follow very specific administration: after an overnight fast, take one pill on an empty stomach with no more than 4 oz/120 mL plain water only, then wait 30 minutes before food, coffee, or other meds
1 If an SGLT2 inhibitor is not tolerated, is contraindicated or if the patient has less than adequate eGFR then it is recommended that a GLP1RA with proven CV benefit should be used
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Refrigerate immediately after each use
