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Purpose of Review: This article summarizes the medical management of obesity with an emphasis on incretin-based therapeutics that target the neuro-hormonal basis of obesity.Recent Findings: Medications that mimic the effect of incretins, a group of peptide hormones released in response to nutrient intake that regulate appetite, result in potent and durable weight loss

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Studies have shown that allulose can attenuate postprandial blood glucose levels, reduce insulin requirements, and even suppress hunger-associated feeding by inhibiting hunger-promoting neurons in the hypothalamic arcuate nucleus (ARC)

Additionally, the loss of fatty acids can affect the skin barrier, leading to dryness and a lacklustre appearance