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Patients with a history of pancreatitis, gallbladder disease, or severe gastroparesis may require careful consideration of risks versus benefits

[DOI] [PMC free article] [PubMed] [Google Scholar] 83.Radwan RM, Lee YA, Kotecha P, Wright DR, Hernandez I, Ramon R, et al

doi: 10.1016/j.bbadis.2018.05.012 127 BruenRCurleySKajaniSCreanDOReillyMELucittMBet al

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[48] They are highly transient, typically peaking during the initial 8-to-12-week dose-escalation phase before waning over time

Significantly lower pricing, particularly below $100, suggests corners are being cut in synthesis, purification, or quality testing