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Description
Recently, Zealand Pharma , a Danish biotechnology company, and Boehringer Ingelheim (BI) announced breakthrough clinical trial results for Survodutide , a novel drug targeting metabolic dysfunction-associated steatohepatitis (MASH)
12 Besides setmelanotide, which is indicated for patients with rare genetic forms of obesity, these alternative anti-obesity medications result in modest weight loss, typically ranging from 3 to 9% of baseline body weight
Conflict of interest The authors declared that this work was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest
These drugs are expensive, insurance coverage is inconsistent, and supply shortages have made them difficult to obtain, even for patients with clear medical needs
miR-192 also decreased GLP-1, promoting T1D
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