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Its half maximal inhibitory concentration (IC50) for GIPR is 42.4 nM, and its EC50 for GLP-1R is 24.4 pM in a human cell-based functional assays (74)

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Glucagon-like peptide-1 and its class BG proteincoupled receptors: a long March to therapeutic successes

This article is not intended to alarm, and it is not intended to discourage anyone from pursuing medical care that may be appropriate for them

The transition from 4mg to 8mg and from 8mg to 12mg represent particularly common windows for constipation onset