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Interestingly, NaB treatment alone (110 mM) had no effect on the FFA-induced increase of TG levels in HepG2 cells (Fig
Nausea, constipation , and fatigue are the most commonly reported issues

Trials to date have focused on weight and metabolic outcomes, with lean mass reduction typically reported as a secondary endpoint and without standardized functional measures

The profound impact on weight management and metabolic health has positioned these drugs as game-changers in the treatment landscape for obesity and type 2 diabetes

In the current investigation, we specifically implemented the Reporting Odds Ratio (ROR) methodology to detect adverse reaction signals, utilizing both the System Organ Class (SOC) and Preferred Term (PT) classifications for the target pharmacological agents

Real-world data tells a different story Interestingly, real-world outcomes look somewhat better than clinical trial results