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The present results suggest that coffee polyphenols may trigger the secretion of GLP-1 from NCI-H716 cells via the cAMP-dependent pathway
Additionally, a 2018 study suggested potential pancreatic cancer protection in individuals with type 2 diabetes who used incretin-based therapies over an extended period

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Many users begin noticing changes within 48 weeks, with gradual progress over several months, depending on consistency and lifestyle