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GLP-1RA can induce glucose-dependent stimulation of insulin secretion, reduce glucagon release, reduce hepatic glucose output, delay gastric emptying and increase satiety, resulting in moderate reductions in glycated hemoglobin (HbA1c), body weight and systolic blood pressure, the risk of hypoglycemia is lower

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95% confidence interval [CI], 0.580.95

It turned out to be a truncated form of the predicted GLP-1, starting with residue no 78 and thus cleaved at a monobasic site

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Circulation 148:A14259 Neumann J, Hofmann B, Dhein S, Gergs U (2023b) Glucagon and its receptors in the mammalian heart