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Glucagon-like peptide-1 (GLP-1) receptor agonists, widely prescribed for type 2 diabetes and weight management, are known for their metabolic benefits but may have unrecognized side effects

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Many of these disorders, including obesity and auto-immune diseases, have been associated with decreased gut barrier function and consequent increased inflammation

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New data from 333,000 patients: 3 years on: 18% risk of heart attack, stroke, death Stop at 12 months: +14% risk Stop at 18 months: benefit fully erased Stop at 24 months: +22% risk It takes 3 years to build it