glp 1 agonist bone density GLP-1 Use Associated with Lower Osteoporosis Risk in Adults with Type 2 Diabetes but Higher Risk in Adults Without Diabetes Impact of GLP- 1 Receptor

JAMA 332(1):8

However, these agents can be expensive for patients whose insurances do not cover the medications

Prescribing information (Eli Lilly, 2024)

Studies of both mice and humans show the anti-inflammatory effects (such as reductions in TNF-) occur within hours, suggesting some actions are independent of weight loss or long-term metabolic change

In addition, liraglutide combined with insulin degludec (IDegLira) is a once-daily, fixed dual combination product approved for T2DM

Effects of semaglutide treatment on psoriatic lesions in obese patients with type 2 diabetes mellitus: An open-label, randomized clinical trial