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doi:10.1001/jama.2014.3628 Murphy CE, Coralic Z, Wang RC, Montoy JCC, Ramirez B, Raven MC

PKA inhibits WNT signalling in adrenal cortex zonation and prevents malignant tumour development

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This ubiquitination competitively inhibits the requisite neddylation of lysine 724 and thus CRL-mediated degradation of pJAK1, prolonging IL-2R signaling and thus maintenance of pSTAT5 expression

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