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But as these drugs are used by millions of patients, unexpected GLP-1 side effects continue to surface from gastrointestinal distress to vision problems and now possibly bone fractures

This is consistent with anecdotal reports showing the increase in semaglutide ADM use being larger in some metropolitan cities than others, and does not always correlate with high diabetes prevalence (Trilliant Health, 2023)

After applying the defined PICOS inclusion and exclusion criteria to select studies directly comparing tirzepatide and semaglutide, a total of 10 studies were deemed eligible for this review

The sectors explosive growth was highlighted by Novo Holdings landmark 13 billion acquisition of Catalent in February 2024, followed by Novo Nordisks 8.7 billion deal to acquire three of Catalents fill-finish sites