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58 Although both peptides showed a helix spanning from Thr 13 to Lys 34 , GLP-1 is less helical than exendin-4 because of Gly at position 22

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Rosas-Ballina et al

Water 14 (2)

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While semaglutide does not directly increase estrogen, weight loss itself improves thermoregulationexcess body fat traps heat and intensifies hot flash severity