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2021;22(Suppl 4):e13256
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Acute Gallbladder Disease In a pool of Study 1 and 2, cholelithiasis was reported in 1.1% of ZEPBOUND-treated patients and 1% of placebo-treated patients, cholecystitis was reported in 0.7% of ZEPBOUND-treated patients and 0.2% of placebo-treated patients, and cholecystectomy was reported in 0.2% of ZEPBOUND-treated patients and no placebo-treated patients
The presence of niacinamide may slow these degradation pathways, extending the viable shelf life of the reconstituted peptide
Additionally, catalase concentrations did not show significant changes in the groups treated with DXN, TIR, or their combination (Figure 6)
