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A: Because reduced kidney reserve makes dehydration, poor intake, blood-pressure changes, and medication interactions more consequential

Trulicity may worsen these conditions

Dirksen C, Jorgensen NB, Bojsen-Moller KN, et al

Acknowledgements The authors would like to thank Emire Bor, EMPIAR Center of Statistical Research and Consulting, for assistance with statistical analysis

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Under high glucose conditions, the phosphorylation level of H3S28ph is significantly reduced, which may lead to a decreased ability for DNA damage repair, thereby exacerbating diabetes-related cellular damage [192]