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Long-term safety data for the specific combination at the specific doses in resM is not available
An analysis published this week in JAMA Internal Medicine found that most participants in a clinical trial who were assigned to stop taking tirzepatide (Zepbound from Eli Lilly) not only regained significant amounts of the weight they had lost on the drug, but they also saw their cardiovascular and metabolic improvements slip away
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As skeletal muscle represents a major site of glucose disposal and systemic energy expenditure [89, 90], its preservation is central to durable metabolic adaptation
Together this clearly indicates that the issue is far from resolved and, considering the potential human life cost, needs urgent attention
[DOI] [PubMed] [Google Scholar] 17.Sato P.Y., Chuprun J.K., Schwartz M., Koch W.J
