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Updated Phase 3 data from December 2025 (TRIUMPH-4 trial) pushed those numbers even higher, with the 12mg dose delivering 28.7% weight loss at 68 weeks, which works out to approximately 71 lb lost on average

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[22] Antiemetic medications may help control nausea in selected patients with persistent symptoms, though this approach should be individualized

In addition, a postweaning androgenization (PWA) model was generated by implantation of subcutaneous capsules containing DHT (10 mg) to female mice after weaning (day 21), thereby allowing chronic androgen exposure up to adulthood

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