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Martell, J

Finally, although the evidence for lifespan expansion in mammalian species is not conclusive, a full analysis and follow-up of clinical trials, including MILES and TAME, may provide more definitive answers as to whether metformin should be promoted beyond its use to treat T2DM, as a drug that enhances both healthspan and lifespan

The researchers completed one-to-one, case-control matching using propensity scores to prevent potential confounding in assessments based on factors including race, ethnicity, age, and type 2 diabetes
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Notably, AGEs deposition is a hallmark feature across all PCOS phenotypes
