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The TRIUMPH-4 trial protocol provides the best reference for effective dosing : Weeks 1-4: 2 mg once weekly (starting dose) Weeks 5-8: 4 mg once weekly Weeks 9-12: 6 mg once weekly Weeks 13-16: 8 mg once weekly Week 17+: 9 mg or 12 mg once weekly (maintenance dose) The escalation happens every 4 weeks, which is slightly faster than many tirzepatide protocols

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Patients taking Mounjaro 15 mg lost an average of 22.5% of their body weight, while patients taking Wegovy 7.2 mg lost around 21%

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Beyond just eating less, the medication improves insulin sensitivity, making it easier for your body to utilize stored fat for energy rather than storing more of it