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Description
The neuroprotective effect of exendin-4 was found to be independent of the glucose-increasing effect, whereas related to increasing the levels of cAMP and reducing oxidative stress and the inflammatory response (83)

Gorelik et al

The future of NAFLD treatment seems exciting and challenging and has the potential to include more personalized and targeted therapeutic approaches, while issues concerning their safety must be thoroughly recorded and appropriately evaluated [42, 43, 138, 144146].

Break through plateaus

For example, in the LEADER trial, liraglutide reduced the incidence of MACE by 13% in T2DM patients at high cardiovascular risk and improved left ventricular function by attenuating systemic inflammation [31]

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